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| Discussing the plerosis on coion injury of ulcerative colitis rats with Chang-an Capsule |
| Hits 1791 Download times 1765 Received:August 29, 2003 |
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| DOI
10.11656/j.issn.1673-9043.2003.04.03 |
| Key Words
Chang-an capsule;ulcerative colitis;experimental research |
| Author Name | Affiliation | | LIU Wan-li | Nanjing Traditional Chinese Medicine Hospital, Nanjing 210001, China | | SHEN Jing-hong | 南京中医药大学附属医院 210029 | | SHAN Zhao-wei | 南京中医药大学附属医院 210029 | | 朱萱萱 | 南京中医药大学附属医院 210029 | | 施荣山 | 南京中医药大学附属医院 210029 |
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| Abstract
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| [Objective]: To ohserve the plerosis on injury of ulcerative colitis rats with Chang-an Capsule and explore its ellect mechanism.[Methods]: The rat model of experimental ulcerative colitis was made hy Immunization and local stimulation.The pathologic change of colonic mucosal tissue was observed under electron microscope and light microscope alter administration.The injury norms,such as colon injury lraction,lactic acid content in stool,prostaglandin E2(PGE2)and so on were detected.[Result]: PGE2 content of colonic tissue,colonic tissue injury fraction and lactic acid content in stool were ohviously reduced.It was also found through tissue pathology that mucosal injury rat was markedly improved in treatment group.[Conclusion]: Chang-an capsule can ellectively alleviate colonic epithelia injury,plerosis injury tissue and promote ulcerative healing. |
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