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| The cholecystic cell ultrastructural change of the Diabetic Rabbits |
| Hits 1462 Download times 1709 Received:April 15, 2004 |
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| DOI
10.11656/j.issn.1673-9043.2004.03.07 |
| Key Words
The rabbits diabetes models;alloxan;the cholecystic microvascular pathological changer |
| Author Name | Affiliation | | CAO Ze-wei | Tianjin NanKai Hospital, Tianjin 300100, China | | LI Fang-ru | Tianjin NanKai Hospital, Tianjin 300100, China | | LI Xiao-hua | 天津市第三中心医院 300140 | | 王志敏 | Tianjin NanKai Hospital, Tianjin 300100, China | | 张洁 | Tianjin NanKai Hospital, Tianjin 300100, China |
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| Abstract
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| [Objective] To observe the cholecystic cell ultrastructural change of the diabetic rabbits induced by Alloxan. [Methods] Twenty-six rabbits were divided randomly into 2 groups:normal group (N group) and the diabetes mellitus group induced by Alloxan (DM group). In DM group,we have controlled the rabbits' blood sugar in 20 mmol/L.We observed the cholecystic cell ltrastructural change of the diabetic rabbits in six weeks. [Result] There were 11 rabbits survived in DM group. We have found cholecystic cell ultrastructural change of the diabetic rabbits in the electron microscope. There were malfunction about cholecystic microvessel, nucleus necrosised,cell plasm partly collapsed,high increased thickness in endothelial cell basal lamina. The cholecystic smooth muscle cell apoptosis and mass marrow phosphorus body between the cell [Conclusion] Rabbits in early DM had the cell ultra structural change in cholecystic microvascular endothelial cell and smooth muscle cell. |
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