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| The influence of Jiuxin capsule on the expression of adhesion molecule from injured endothelium cell by hypoxia |
| Hits 1999 Download times 1639 Received:March 11, 2004 |
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| DOI
10.11656/j.issn.1673-9043.2004.03.08 |
| Key Words
Jiuxin capsule;adhesion molecule;endothelium cell;hypoxia |
| Author Name | Affiliation | | LI Chun-shen | Tianjin University of TCM, Tianjin 300193, China | | CEHN jing | Tianjin University of TCM, Tianjin 300193, China | | FAN Ying-chang | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] The mechanism of Jiuxin capsule on coronary heart disease (CHD) through observing the influence of Jiuxin capsule on the expression of adhesion molecule from injured endothelium cell by hypoxia.[Methods] Through cultivating endothelium cell in vitro,the expression of adhesion molecule (VCAM-1,ICAM-1) in cytoplasm was observed by immunochemistry in hypoxia injured endothelium cell.[Result] The expression of adhesion molecule increased markedly after endothelium cell was injured by hypoxia,and Jiuxin capsule coul inhibit.[Conclusion] Jiuxin capsule can marked1y decrease the expression of adhesion molecule of endothelium cell and protect the endothelium cell against injured by inflammation mediater. |
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