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| Protectivse Mechanism of Salviol Acid B against Acute Myocardial Ischemia/Reperfusion Injury in Rats |
| Hits 1561 Download times 1550 Received:April 12, 2004 |
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| DOI
10.11656/j.issn.1673-9043.2004.03.10 |
| Key Words
myocardial injury;ischemia/reperfusion; Salviol acid B;rat |
| Author Name | Affiliation | | WANG Baohe | The Second Hospital Affiliated to Tianjin University of TCM, Tianjin, 300150 | | FU Wei | 天津市建筑设计院 300150 | | LI Zhuting | The Second Hospital Affiliated to Tianjin University of TCM, Tianjin, 300150 |
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| Abstract
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| [Objective] The present study was designed to investigate the protective mechanism of Salvoid acid B against acute myocardial injury induced by ischemia/reperfusion in rats.[Methods] Experimental animals were randomized to 5 groups,receiving sham operation,model preparation,Captopril,FufangDanshen Pian (Tablet of complex prescription of Radix Salviae Miltiorrhizae),and Salviol acid B respectively.[Results] Salviol acid B Could decrease the plasma level of AF-1,ET,TXA2 TNF and Ca2+ and increase PGI2 and SOD in rats.Its action was markedly superior to that in FufangDanshen Pian and model group. (P<0.05). [Conclusion] Salviol acid B possesses better protective effect for myocardial cell during ischemia/reperfusion. |
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