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Sarcoma by Fufangkushen Injection Experimental Study on Inhibiting Angiogenesis in Mice S180 |
Hits 1727 Download times 1684 Received:January 08, 2006 |
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DOI
10.11656/j.issn.1673-9043.2006.01.11 |
Key Words
Fufangkushen injection;Tumor;Anti-angiogenesis |
Author Name | Affiliation | Jia Ying-jie | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193 China | Zhang Ying | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193 China | Shi Fu-min | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193 China |
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Abstract
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[Objective] To investigate the effect of inhibiting angiogenesis by Fufangkushen Injection.[Methods] The experimental treatment in mice tumor model observe inhibiting angiogenesis in mice S180 sarcoma by Fufangkushen Injection by immunohistochemistry.[Results] Mice were intraperitoneally injected with Fufangkushen Injection of 0.3,0.6 g/kg.After 8 days,tumor weights diminish 25%,36% compared with the control group.The vascular density of S180 sarcoma diminish 32%,40% compared with the control group.[Conclusion] Fufangkushen Injection have inhibitory effect on S180 sarcoma and strong inhibitory effects on angiogenesis. |
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