|
The influence of salvianolic acid B and tanshinone ⅡA on the nitric oxide and triglyceride in sera of atherosclerosis rabbits |
Hits 1546 Download times 2010 Received:December 02, 2005 |
View Full Text View/Add Comment Download reader |
DOI
10.11656/j.issn.1673-9043.2006.01.14 |
Key Words
red sage root;salvianolic acid B;tanshinoneⅡA;atherosclerosis;nitric oxide;triglyceride |
Author Name | Affiliation | LV Bing-qiang | Tianjin University of TCM Tianjin 300193 China | FAN Ying-chang | Tianjin University of TCM Tianjin 300193 China | SUN Lian-sheng | 天津市塘沽区杭州道医院 300354 |
|
Abstract
|
[Objective] To study the influence of water-soluble active principle (salvianolic acid B) and fat-soluble active principle (tanshinoneⅡA) on the level of nitric oxide (NO) and triglyceride (TG) in sera of atherosclerosis rabbits.[Methods] Atherosclerosis was initiated in rabbits by feeding cholesterol and oil.The influence of salvianolic acid B and tanshinoneⅡA on sera NO and TG were observed by radio immunity and GPO-PAP.[Results] Both of the salvianolic acid B and the tanshinoneⅡA could markedly decrease the level of TG and significantly increase the NOW but the tanshinoneⅡA was significantly better than the salvianolic acid B on NO,the salvianolic acid B was better significantly better than the tanshinoneⅡA on TG.[Conclusion] The salvianolic acid B and tanshinoneⅡA both could inhit atherogenesis of hyperlipid-fed rabbits by modulate the NO and TG,but the mechanism is not entire the same. |
|