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| The Clinical Study of Hugantang in the Treatment of Liver Desease Induced by Drugs |
| Hits 1441 Download times 1679 Received:December 08, 2005 |
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| DOI
10.11656/j.issn.1673-9043.2006.03.21 |
| Key Words
hugantang;antipsychotics;Drug-induced liver decease |
| Author Name | Affiliation | | ZHOU Zhen | Tianjin An Kang Hospital, Tianjin 300240, China | | FU Rong | Tianjin An Kang Hospital, Tianjin 300240, China | | HUANG Ping | Tianjin An Kang Hospital, Tianjin 300240, China |
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| Abstract
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| [Objective] To explore the efficacy of Hugantang in treating hepatic damage induced by antipsychotics.[Methods] Fifty-five cases of psychiatric patients with hepatic damage induced by antipsychotics were randomly divided into two grups, the experimental group (n=28), treated by Hugantang. Twenty-seven cases in control group, treated by Tiopronin. After that, some clinic symptom and biochemical indexes reflecting liver function were observed and compared for 4 weeks.[Results] Four-Week treatment later, clinic symptom, AST, ALT as well as their recovery rates in treatment group were equal to those in the control group(P>0.05). The significantly effective rate and the overall effective rate in the treatmentgroup were 64.3%. and 92.9%, respectively, which were 63.0% and 96.3% respectively, in control group.[Conclusions] Hugantang can decrease the level of AST, ALT and has more effective in the treatment of hepatic damage induced by antipsychotics. |
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