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Influnence of Yangan Roujin Prescription on F-Trp and 5-HT Levels of Blood and Brain in Exercise-induced Central Fatigue Rats
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DOI   10.11656/j.issn.1673-9043.2006.04.13
Key Words   Yanggan Roujin Prescription;F-Trp;BCAA;5-HT;exercise-induced central fatigue
Author NameAffiliation
WANG Fang Tianjin University of TCM, Tianjin 300193, China 
SHI Li-ping Tianjin University of TCM, Tianjin 300193, China 
MA Zuo-ying Tianjin University of TCM, Tianjin 300193, China 
何山 天津市开发区医院 300357 
毕慧娟 Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To explore the effect of Yanggan Roujin Prescription (YGRJF) on eliminating exercise-induced central fatigue.[Methods] Using YGRJF on rat model of swimming training-induced central fatigue,observed the changes on the content of plasma FFA and the ratio of F-Trp/BCAA,the levels of brain tissue F-Trp,5-Htand and 5-HIAA in central fatigue rat.[Results] Compared with the training rats in control group,in the training group ingesting YGRJF the content of plasma FFA and BCAA have the upward trend,but the content of brain tissue F-Trp obviousely down regulate.[Conclusion] YGRJF can chang osmosis of blood-brain barrier and stave off the central fatigue occurrence by stabilizing the concentration of plasma FFA and BCAA to a certain extent,reducing the ingestion of brain F-Trp.

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