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Comparative study between pharmacodynamics and contents of active components in extracts of Kang-gan compound with different method
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DOI   10.11656/j.issn.1673-9043.2007.02.07
Key Words   kanggan compound;extracts, active component;anti-pyretic and anti-inflammatory effect
Author NameAffiliation
LI Jin Tianjin University of TCM, Tianjin 300193, China 
WANG Jian Tianjin University of TCM, Tianjin 300193, China 
ZHONG Pei-ru Tianjin University of TCM, Tianjin 300193, China 
高岚 Tianjin University of TCM, Tianjin 300193, China 
苗戎 Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To compare the content of active component of different extracts from Kanggan (anti-common cold) Compound and their anti-pyretic effect and anti-inflam matory effect.[Methods] Taking aspirin or dexam ethasone as the positive control medicine and reproducing experimental fever in rats with yeast,edema of paw metatarsus with carrageeninin in rats and cotton-ball granuloma in rats to investigate the anti-pyretic and anti-inflam matory effect of the different extracts.[Results] The water extracts showed a significant anti-pyretic and anti-inflam matory effect,and the water extract dealt with ZTC 1+1,a floccule coagulating preparation,showed a more marked anti-pyretic effect.[Conclusions] The evaluation of the extract method from the content of the active component only is not a completed.

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