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Examination of optimum technique and dissolution time for Shuanghuanglian Dripping Pill
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DOI   10.11656/j.issn.1673-9043.2007.02.10
Key Words   Shuanghuanglian Dripping Pill;preparation;dissolution limit
Author NameAffiliation
ZHOU Li-ling Tianjin University of TCM, Tianjin 300193, China 
ZHANG Shi-yu Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To optimize the best technique for preparation of Shuanghuanglian (double coptis chinensis) Dripping Pill and to determine its dissolution limit.[Methods] The matrix,the proportion of the matrix and medicine,the temperature of its production and the temperature of condensation preparation of the dripping pill were screened.The dissolution limit was examined with dissolution instrument.[Results] The best technique of Shuanghuanglian was that one portion of water dissolved matrix served as the matrix,the proportion of medicine and matrix was 1:2,pill-producing temperature was 70℃,the used temperature of condensation preparation was 0-5℃.It was showed that the Shuanghuanglian could be fully dissolved within 6 minutes.[Conclusions] The technique for preparation of Shuanghuanglian Dripping Pill is reasonable and the dissolved limit is met with the requirement.

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