|
| Effect of the combination of Sal B and PNS on left ventricular construction and function of rats with myocardial infarction |
| Hits 2083 Download times 1832 Received:April 02, 2007 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2007.03.13 |
| Key Words
Salvianolic acid B;panax notoginseng saponins;compatibility;left ventricular;myocardial infarction |
| Author Name | Affiliation | | ZHANG Meng | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | GAO Xiu-mei | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | WANG Yi | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | 徐强 | 天津中医药大学第二附属医院 300150 | | 张伯礼 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
|
| Abstract
|
| [Objective] In order to elucidate the scientific connotation of compatibility in traditional Chinese medicine (TCM) formulas,we observed the effects of Salvianolic acid B (Sal B) and panax notoginseng saponins (PNS) used alone and in combination on rats with acute myocardial infarction.[Methods] To produce myocardial infarction in anaesthetized rats by occluding the left descending coronary artery.Sham-operated rats served as controls.To assayed the construction and function of left ventricular by using echocardiography.[Results] Sal B,PNS and the combination of Sal B and PNS can decrease LVDs,LVESV and increase EF and FS. There was a trend that the effects of the combination of Sal B and PNS were better than others.[Conclusion] The combination of Sal B and PNS can improve the heart function effectively. |
|
