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Study of hypersensitivity,stimulation on blood vessel,and hemolysis of Xueshuantong Sodium Chloride Injection |
Hits 1999 Download times 1785 Received:December 02, 2007 |
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DOI
10.11656/j.issn.1673-9043.2008.02.08 |
Key Words
Xueshuantong Sodium Chloride Injection;hypersensitivity;stimulation;hemolysis;rabbit;guinea-pig |
Author Name | Affiliation | CHEN Li-jiang | School of Pharmacy, Liaoning University, Shenyang, Liaoning 110036, China | ZHANG Sheng | 辽宁省医药工业研究院 110015 | MENG Fan-rui | School of Pharmacy, Liaoning University, Shenyang, Liaoning 110036, China | 王欣 | School of Pharmacy, Liaoning University, Shenyang, Liaoning 110036, China | 刘冰弥 | School of Pharmacy, Liaoning University, Shenyang, Liaoning 110036, China | 李丽 | School of Pharmacy, Liaoning University, Shenyang, Liaoning 110036, China | 刘宇 | School of Pharmacy, Liaoning University, Shenyang, Liaoning 110036, China |
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Abstract
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[Objection] To observe the hypersensitivity, stimulation on blood vessel, and hemol-ysis of Xueshuantong Sodium Chloride Injection. [Methods] The hypersensitive reaction on guinea-pig, the stimulation reaction on blood vessel of rabbit, and the hemolysis and agglomeration reaction on vitro-body red cell of rabbits of Xueshuantong Sodium Chloride Injection were studied. [Results] Xueshuantong Sodium Chloride Injection, 10 mL/kg, iv, once a day for seven days, showed no hypersensitive action on guinea-pig, no stimulation on blood vessel of rabbits, no hemolysis and agglomeration on vitro-body red cells of rabbits. [Conclusion] Xueshuantong Sodium Chloride Injection has no hypersensitivity, stimulation on blood vessel and hemolysis. |
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