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Interference of tonifying qi, activating blood and dispersing accumulation on pulmonary fibrosis and the mechanism research
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DOI   10.11656/j.issn.1673-9043.2008.03.23
Key Words   pulmonary fibrosis;the method of tonifying Qi,activating blood and dispersing accumulation;TGF-β1
Author NameAffiliation
SUN Zeng-tao The Second Hospital Affiliated to the Tianjin University of TCM, Tianjin 300150, China 
FENG Ji-hong The Second Hospital Affiliated to the Tianjin University of TCM, Tianjin 300150, China 
LI Xiao-juan The Second Hospital Affiliated to the Tianjin University of TCM, Tianjin 300150, China 
廉富 The Second Hospital Affiliated to the Tianjin University of TCM, Tianjin 300150, China 
刘恩顺 The Second Hospital Affiliated to the Tianjin University of TCM, Tianjin 300150, China 
Abstract
    [Objective] To explore the intervention effect of tonifying Qi,activating blood and dispersing accumulation method on pulmonary fibrosis and analyze its mechanism.[Methods] A systematic clinical observation and animal experimental study on the effect of tonifying Qi,activating blood and dispersing accumulation on pulmonary fibrosis and their mechanism research were carried out.[Results] The method of tonifying Qi,activating blood and dispersing accumulation could not only improve the patients'symptoms obviously,but also inhibit the inflammation in lung alveoli,reduce TGF-β1 over-expression.[Conclusion]The method of tonifying Qi,activating blood and dispersing accumulation can improve the patients'symptoms,and play an important role in preventing and curing pulmonary fibrosis.

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