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A systematic assessment on the clinical controlled trial in treating pulse-arrhythmia and heart-palpitation with Zhigancaodecoction and Its modified prescription |
Hits 1901 Download times 2579 Received:June 11, 2008 |
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DOI
10.11656/j.issn.1673-9043.2008.04.04 |
Key Words
Zhigancao decoction;pulse-arrhythmia;heart-palpitation;clinical controlled trial;systematic assessment |
Author Name | Affiliation | SONG Jun-sheng | Tianjin University of TCM, Tianjin, 300193, China | WU Xi-qing | Tianjin University of TCM, Tianjin, 300193, China | LU Xiao-zuo | Tianjin University of TCM, Tianjin, 300193, China | 熊俊 | Tianjin University of TCM, Tianjin, 300193, China |
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Abstract
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[Objective] To systematically assess the clinical controlled trial in treating pulse-ar-rhythmia (irregularly intermittent and regularly intermittent) and heart-palpitation (severe palpitation) with Zhigancao decoction and its modified prescription in order to providing a theoretic foundation for further perfecting the designing of clinical investigation of Zhigancao decoction. [Methods] The clinical controlled trials of Zhigancao decoction and its modified prescriptions in treating the pulse-arrhythmia and heart-palpitation were collected and the qualified research in them was selected.Their quality evaluation was performed by using the Cochrane system estimation manual of 4.2.2 edition about RCT.[Results] Thirty clinical controlled trials were found,among them the research finished in a single-center were 30.According to the assessing standard of Cochrane,all articles belonged to scale C.[Conclusion] From these available researches it is considered that the effects of Zhigancao decoction and its modified prescriptions in treating pulse-arrhythmia and heart-palpitate were more superior than that of the control group.But the quality of the literatures was not so high generally.Much more clinically controlled trials with high quality were expected. |
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