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| Effect of different matching of salvianolic Acid B and panax Pseudo-ginseng total saponin on coronary artery flow of isolated heart in rats |
| Hits 1822 Download times 1749 Received:August 28, 2008 |
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| DOI
10.11656/j.issn.1673-9043.2008.04.11 |
| Key Words
salvianolic acid B;panax pseudo-ginseng total saponin;isolated heart |
| Author Name | Affiliation | | LI Yu-hong | Tianjin University of TCM, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin 300193, China | | XU Qiang | 天津中医药大学第二附属医院 300150 | | GAO Xiu-mei | Tianjin University of TCM, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin 300193, China | | 胡利民 | Tianjin University of TCM, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin 300193, China | | 张伯礼 | Tianjin University of TCM, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the effect of different matching of salvianolic acid B combined with and panax pseudo-ginseng total saponin on coronary artery flow of isolated heart in rats.[Methods] Six levels of different matching of salvianolic acid B and panax pseudo-ginseng total saponin were designed.Constant pressure perfusion of isolated heart was carried out by using Langendorff system and the coronary artery flow rate was recorded.[Results] There wasn't linear regression relation in enhancing coronary artery flow rate when salvianolic acid B and panax pseudo-ginseng total saponin were used.The 20 mg:30 mg dosage group was the best for increasing the coronary artery flow rate in rats.[Conclusion] Different matching of salvianolic acid B and panax pseudo-ginseng total saponin has a tremendous effect on coronary artery flow rate of isolated heart in rats. |
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