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| Effects of salvianolic acid B on conglutination,migration and proliferation of endothelial progenitor Cells (EPCs) in vitro |
| Hits 1509 Download times 1116 Received:August 10, 2008 |
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| DOI
10.11656/j.issn.1673-9043.2009.01.08 |
| Key Words
Key words salvianolic acid B (SaIB);endothelial;progenitor cels (EPCs);conglutination;migration;proliferation |
| Author Name | Affiliation | | LI Qing-wen | Tianjin Institute of Physical Education, Tianjin 300381, China | | NAN Ya-yun | 天津中医药大学 300193 | | JIANG Xi-juan | 天津中医药大学 300193 | | 谭俊珍 | 天津中医药大学 300193 | | 范英昌 | 天津中医药大学 300193 |
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| Abstract
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| [Objective] To invistigate the effects of Salvianolic acid B on conglutination,migration and proliferation of Endothelial.Progenitor Cells (EPCs) In Vitro.[Methods] Cultivation and purification of EPCs in vitro was by density-gradient centrifugation and plastic adherence method,and identified by immunofluorescence and immunocytochemistry (CD34/CD,133).The conglutination,migration and proliferation of EPCs were examined by DiI stain,Transewell and DAPI stain and Brdu immunofluorescence and immunocytochemistry method respectively.[Results] The Cell count of conglutination was (37.00±3.27),those of migration at 24 horus and 48 hours were (26.32±2.66) and (53.41±3.85) respectively and that of proliferation was (41.17±3.43),which increased remarkably comparing with the control group.[Conclusion] Salvianolic acid B could improve markedly the conglutination,migration and proliferation ability of Endothelial Progenitor Cells (EPCs) In Vitro. |
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