|
| Serum isolated calcium ievel in mice with syndrome of bloodstasis induced by cold coagulation and heat toxicity and intervention of TCM |
| Hits 1859 Download times 1650 Received:December 18, 2009 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2010.02.12 |
| Key Words
Wen Jing decoction;Qing Ying decoction;animal model;syndrome of blood stasis;whole blood viscosity;serum isolated calcium |
| Author Name | Affiliation | | WANG Xue-ling | | | LU Yi-zhu | | | CHEN Xiao-xu | | | 张筠 | | | 孙蕊 | |
|
| Abstract
|
| [Objective] To explore the biologic basis of blood stasis in TCM through investigating the correlation of serum isolated calcium and blood stasis induced by cold coagulation and heat toxicity and further explore the intervention effect of some Chinese herbs.[Methods] Eighty rats were divited into 5 groups.After inducing blood stasis each group was treated with corresponding decoction of Chinese herbs.The whole blood viscosity and serum isolated calcium were determined at the end of experiment.[Results] Both the whole blood viscosity and serum isolated calcium were all increased after inducing disease.The whole blood viscosity under every shear rate and serum isolated calcium in the blank control group and medication group were all different significantly when compared with blood stasis group. (P<0.01 or P<0.05).[Conclusion] The developing mechanism of the syndrome of blood stasis in TCM has a definite correlation with the serum isolated calcium.Simultaneously,Chinese medication can significantly decrease the blood viscosity in rats with syndrome of blood stasis.This can provide the theoretic and experimental evidence for increasing the effect of diagnosing and treating blood stasis-correlating diseases. |
|
