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| Clinical observation on Fuzheng Huayu capsule in treating hepatic fibrosis of patients with chronic hepatitis B |
| Hits 2062 Download times 2046 Received:April 11, 2010 |
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| DOI
10.11656/j.issn.1673-9043.2010.03.09 |
| Key Words
chronic hepatitis B;liver fibrosis;Fuzheng Huayu capsule |
| Author Name | Affiliation | | Wang Hong-xia | Tianjin HanGu Hospital, Infectious Diseases Departmen, Tianjin 300480, China |
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| Abstract
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| [Objective] To observe the change of clinical symptoms,signs,liver function,serum hepatic fibrosis indices in patients of chronic hepatitis B with liver fibrosis before and after treatment with Fuzheng Huayu (Tonifying vital QI and Removing stasis) capsule.[Methods] Twenty-seven patients in treatment group were treated with Fuzheng Huayu capsule manufactured in Shanghai University of Traditional Chinese Medicine Research Institute,1.5 g,three times a day.25 patients in control group were treated with conventional protective liver therapeutics.Both groups were treated for three months.[Result] Fuzheng Huayu capsule could effectively improve the clinical symptoms and signs in patients with chronic hepatitis B and restore the liver function.The effects are same with the drugs having a significant role to protect liver and reduce enzymes.Fuzheng Huayu Capsule had obvious protective effects against liver fibrosis.After treatment,serum hyaluronic acid (HA) ,laminin (LN) ,Ⅲprocollagen (PC-Ⅲ) ,Ⅳcollagen (Ⅳ-C) were all significantly reduced,with significant difference.[Conclusion] Fuzhenghuayu capsule can not only express liver-protecting effect,but also have the effect of certain anti-liver fibrosis. |
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