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| Research on time-effect relationship of adverse reaction of Xiao Yan Tang in treating patients with non-small cell lung cancer with Qi deficiency and toxic stasis |
| Hits 2249 Download times 1939 Received:September 28, 2010 |
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| DOI
10.11656/j.issn.1673-9043.2010.04.08 |
| Key Words
Xiao Yan tang;non-small cell lung cancer;chemotherapy;dosing time |
| Author Name | Affiliation | | JIA Ying-jie | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medcine, Tianjin 3001093, China | | LI Xiao-jiang | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medcine, Tianjin 3001093, China | | YANG Pei-ying | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medcine, Tianjin 3001093, China | | 张莹 | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medcine, Tianjin 3001093, China | | 张蕴超 | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medcine, Tianjin 3001093, China | | 黄敏娜 | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medcine, Tianjin 3001093, China | | 包芳芳 | 天津中医药大学 300193 |
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| Abstract
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| [Objective] To observe the clinical therapeutic effect of the time-effect relationship of Xiao Yan Tang in treating patients with non-small cell lung cancer with Qi deficiency and blood stasis.[Methods] 60 patients with non-small cell lung cancer were randomly divided into a chemotherapy group with 7 days ahead of giving,group with 3 days ahead of using of Xiao Yan Tang combined with chemotherapy,chemotherapy group combined with Xiao Yan Tang and group with chemotherapy only.The myelosuppression,liver and kidney function,adverse effect on gastrointestinal tract and the quality of life were compared between these four groups.[Results] Compared with the group of chemotherapy only,Xiao Yan Tang could significantly improve the toxicity on white blood cell,ameliorate the gastrointestinal symptoms of nausea and vomiting,increase the quality of life of patients.The best therapy could be seen at 7 days ahead of using of Xiao Yan Tang.There was no,however,significant effect on decreasing of NE,HGB and PLT,stomatitis,symptoms of diarrhea and constipation,liver toxicity,urinary system toxicity.[Conclusion] Xiao Yan Tang has good effect on relieving the chemotherapy side effects in patients with non-small cell lung cancer with Q deficiency and blood. |
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