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Effect of Huoxue Huayu plaster on hyaluronic acid of articular serum in osseous arthropathy of knee with observation in 30 patients
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DOI   10.11656/j.issn.1673-9043.2011.01.07
Key Words   OA of knee;Huoxue Huayu plaster;hyaluronic acid
Author NameAffiliation
LI Zhuo The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
WANG Ping The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To observe the effectiveness of external using of Huoxue Huayu (activating blood circulation and removing stasis) plaster in treating osseous arthropathy of knee (OA) due to syndrome of kidney deficiency and blood stasis and the effect on hyaluronic acid concentration (SF-HA) in articular serum.[Methods] The change of HA in SF was determined before and after treatment with Huoxue Huayu plaster.Simultaneously, auxiliary evaluation was performed with Lysholm score standard of knee article function in 30 patients.Statistical analysis was finished with SPSS 11 soft wire.[Results] When treating OA of knee with Huoxue Huayu plaster the difference before and after therapy was significant (P<0.05),The concentration of SF-HA after treatment was obviously higher than that before.The evaluated function of knee article with Lysholm was compared before and after therapy and P<0.05 was obtained.The obvious effective ratio before and after was 100%.[Conclusion] SF-HA is a biochemical marker responding the metabolic change of OA.It is mainly influenced by the severity extent of OA in knee having a negative correlation.External using of Huoxue Huayu plaster can significantly improve the clinical symptom and signs in OA of knee.

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