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Effect of electro-acupuncture and collateral circulation re-establish in early stage of cerebral infarction
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DOI   10.11656/j.issn.1673-9043.2011.02.12
Key Words   cerebralinfarction;MCAO;collateralcirculation;electro-acupuncture
Author NameAffiliation
LI Gui-ping The First Hospital Affiliated to Tianjin University of TCM, Tianjin 300193, China 
SHI Lei The First Hospital Affiliated to Tianjin University of TCM, Tianjin 300193, China 
DU Yuan-hao The First Hospital Affiliated to Tianjin University of TCM, Tianjin 300193, China 
李颖 天津中医药大学 300193 
Abstract
    [Objective] To research the effect of the collateral circulation re-establish in semi-dark area and electro-acupuncture in the early stage of acute cerebral infarction ischemia in rats with MCAO induced by thread occlusion. The acute cerebral infarction in rat was induced by middle cerebral artery occlusion. [Methods] Using Lectin Histochemistry stain technique the changing of the blood vessel in the penumbra was observed and the effect of electro-acupuncture stimulus on blood vessel count at 1, 3, 6 hours after MCAO was evaluated. [Results] Lectin Histochemistry stain technique was used to reveal the morphological changing of the blood vessel After MCAO. Compared with normal brain, the blood vessel count were reduced in the penumbra (P <0.001). After electro- acupuncture stimulus, blood vessel count was raised in the peri-ischemic zone (P<0.05) at 1,3,6 hours after MCAO. [Conclusion] Electro-acupuncture stimulus can significant increase the blood vessel count in the peri-ischemic zone and promote the establishment of collateral circulation after MCAO.

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