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| Observation on curative effect of Shensong Yangxin capsules in chronic heart failure |
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| DOI
10.11656/j.issn.1673-9043.2011.03.09 |
| Key Words
chronic heart failure(CHF);Shensong Yangxin capsules;the function of left ventricle sinister;exercise tolerance |
| Author Name | Affiliation | | CHEN Wei-yun | Zhongshanmen Community Medical Care Center, Tianjin 300181, China
| | WANG Yu | Tianjin Third Central Hospital, Tianjin 300171, China |
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| Abstract
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| [Objective] To investigate the curative effect of Shensong Yangxin capsules in treating chronic heart failure (CHF).[Methods] The 100 CHF patients due to different causes were randomly divided into two groups:the control group (48 cases) treated with the conventional therapies including digitalis,diuretics,angiotensin-converting enzyme inhibitors and so on;Shensong Yangxin capsules group(52 cases)treated with Shensong Yangxin capsules and the conventional therapies described above.The course of treatment was 3 months.The curative effect,left ventricular end-diastolic dimension (LVEDD),left ventricular ejection fraction (LVEF),B-type natriuretic peptide (BNP),walking distance in 6 minutes and so on were observed.[Results] After treatment,the total effective rate of Shensong Yangxin capsules group was obviously higher than that in the control group (P<0.05).LVEDD and BNP of Shensong Yangxin capsules group were obviously lower than those in the control group as well as before treatment,showing a significant difference (P<0.05 or P<0.01).LVEF and walking distance in 6 minutes of Shensong Yangxin capsules group were obviously increased,and there was a significant difference as compared with the control group as well as before treatment (P<0.05 or P<0.01).[Conclusion] It is suggested that Shensong Yangxin capsules can obviously improve the function of left ventricle,increase the exercise tolerance,decrease the concentration of BNP,and they are safety for the CHF patients. |
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