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Establishment of scald model in rats
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DOI   10.11656/j.issn.1673-9043.2011.04.09
Key Words   scald;temperature;time;pressure
Author NameAffiliation
WANG Xue-ni Tianjin University of TCM, Tianjin 300193, China 
ZHANG De-qin Tianjin University of TCM, Tianjin 300193, China 
HUANG Yun-ying Tianjin University of TCM, Tianjin 300193, China 
王元元 Tianjin University of TCM, Tianjin 300193, China 
沈丽 Tianjin University of TCM, Tianjin 300193, China 
杜娟 Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To establish scalding models of deep Ⅱ,superficial Ⅱ and Ⅰ of body surface in Wistar rats for research of scalding repair.[Methods] Using homothermic and pressure-stable temperature controlled apparatus and setting different scald conditions in three models of scald with the same dimension,degree-different of skin damage.The pathologic examination was also performed.[Results] The deep Ⅱ of scalding in rats could be induced with temperature 90℃,scalding time 15 s,pressure 1 000 g;superficial Ⅱ with 80℃,15 s and pressure 1 000 g and Ⅰ with 80℃,10 s and pressure 500 g.[Conclusion] The scald degree is influenced by temperature,time and pressure,especially by temperature.The scalding depth and area in this model can be controlled.The result shows that it is an ideal model of skin scald.

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