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Change of syndrome type of TCM in patients with upper respiratory tract infection before and after antibiotics treatment
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DOI   10.11656/j.issn.1673-9043.2012.01.07
Key Words   upper respiratory tract infection;antibiotics;syndrome;cluster analysis;tongue picture
Author NameAffiliation
YANG Xiao-huan The First Affiliated Hospital of Shantou Medical College, Shantou University, Shantou 515041, China 
ZHANG Min The First Affiliated Hospital of Shantou Medical College, Shantou University, Shantou 515041, China 
JI Xuan The First Affiliated Hospital of Shantou Medical College, Shantou University, Shantou 515041, China 
WANG Chun-yang The First Affiliated Hospital of Shantou Medical College, Shantou University, Shantou 515041, China 
YAO Hai-hong The First Affiliated Hospital of Shantou Medical College, Shantou University, Shantou 515041, China 
ZHANG Ling-ling The First Affiliated Hospital of Shantou Medical College, Shantou University, Shantou 515041, China 
Abstract
    [Objective] To observe the change of syndrome type of TCM in patients with upper respiratory tract infection before and after antibiotics treatment.[Methods] We observed tongue picture and the change of symptoms in 86 cases with upper respiratory infection before the treatment and 3 days and 6 days after treatment,recorded the symptoms and the scores.A course was 6 days.Using statistics cluster analysis method to deal with new added symptoms,the relative TCM syndromes were ascertained.Using picture software to handle the tongue picture the dependability with TCM syndromes was determined.[Results] TCM syndrome distribution of upper respiratory tract infection before treatment was:wind-cold syndrome in 28 cases,wind-heat syndrome in 27 cases,wind-cold with damp syndrome in 2 cases,wind-heat with damp syndrome in 19 cases.The TCM syndrome distribution 3 days after treatment was:wind-cold syndrome in 2 cases,wind-heat syndrome in 3 cases,wind-cold with damp syndrome in 36 cases,wind-heat with damp syndrome in 45 cases.The TCM syndrome distribution 6 days after treatment was:wind-cold syndrome in 2 cases,wind-heat syndrome in 1 case,wind-cold with damp syndrome in 27 cases,wind-heat with damp syndrome in 56 cases.The cluster analysis showed that there were two syndromes of damp-heat stagnating in the spleen and cold-damp invasion of spleen.Compared with the syndromes scores at third day,the scores of cold-damp invasion of spleen syndrome and damp-heat stagnating in the spleen syndrome 6 days after treatment had significant difference (P<0.05).The value of coated tongue R,G,and B in patients with cold-damp invasion of spleen syndrome was all less than that in damp-heat stagnating in the spleen syndrome.[Conclusion] The patients with upper respiratory tract infection after antibiotics treatment were mainly changed to damp-heat stagnating in the spleen syndrome and cold-damp invasion of spleen syndrome,suggesting using Chinese traditional medicine with corresponding antibiotics for treatment.

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