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Effects of honey and propolis on wound healing in rats with second-degree scald
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DOI   10.11656/j.issn.1673-9043.2012.03.08
Key Words   honey;propolis;external application;scald;wound healing
Author NameAffiliation
WANG Yuan-yuan The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China 
HUANG Yun-ying The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China 
DU Juan The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China 
SHEN Li The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China 
ZHANG De-qin The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China 
WANG Xue-ni The TCM Research Institute, Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To investigate the effects of honey and propolis on wound healing in rats with second- degree scald.[Methods] Second-degree scald on the back of rat was induced by scald-reproducing instrument with super-temperature control(YLS-5Q).The rates of wound healing and histological changes were observed.The level of hydroxyproline(HYP)and superoxide dismutase(SOD)in serum were determined by ELISA.[Results] The rates of wound healing in treatment group were increased compared with the control group(P<0.01).The levels of HYP and SOD in treatment group were higher than that in the control group(P<0.01 or P<0.05).[Conclusion] Honey and propolis has a promoting effect on burn wound healing by its external application.

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