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| Study on chemical components of Steroidal Saponins from Tribulus terrestris L. |
| Hits 2882 Download times 2590 Received:September 29, 2012 |
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| DOI
10.11656/j.issn.1673-9043.2012.04.11 |
| Key Words
Tribulus terrestris L.;steroidal saponins;isolation and purification;structural elucidation |
| Author Name | Affiliation | | WU Ke-lei | Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China
Tianjin University of TCM, Tianjin 300193, China | | KANG Li-ping | Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China
Tianjin University of TCM, Tianjin 300193, China | | XIONG Cheng-qi | Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China | | ZHAO Yang | Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China | | YU He-shui | Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China
Tianjin University of TCM, Tianjin 300193, China | | ZHANG Jie | Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China | | MA Bai-ping | Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China |
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| Abstract
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| [Objective] To investigate the chemical components of the herb Tribulus terrestris L. [Methods] The chemical components were isolated through column chromatography on macroporous resin (SP825), silica gel, octadecyl silica (ODS) columns and PHPLC. Their structures were identified by physicochemical properties and spectra data. [Results] Five steroidal saponins were obtained from Tribulus terrestris L. They were uttroside B (1), polianthoside (2), tigogenin-3-O-β-D-xylopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-galactopyranoside (3), (25R)-26-O-β-D-glucopyranosyl-5α-furost-12-one-3β, 22α, 26-triol-3-O-β-D-gluco-pyranosyl-(1→4)-β-D-galactopyranoside (4) and hecogenin-3-O-β-D-glucopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside (5). [Conclusion] Compounds 1 and 2 were obtained from Tribulus terrestris L. for the first time. |
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