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| Study of Yixin Dingji prescription medicated serum on the expression of VEGF in human umbilical vein endothelial cell |
| Hits 1856 Download times 1500 Received:February 15, 2013 |
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| DOI
10.11656/j.issn.1673-9043.2013.02.08 |
| Key Words
Yixin Dingji prescription;human umbilical vein endothelial cell;VEGF |
| Author Name | Affiliation | E-mail | | YU Xiao-hong | The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | YANG Ying | The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China | woairentianjian@163.com | | ZHOU Ya-bin | The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China | |
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| Abstract
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| [Objective] By observation of Yixin Dingji prescription on human umbilical vein endothelial VEGF expression to explore its treatment of coronary heart disease tachyarrhythmia mechanism and provide an objective basis for clinical application. [Methods] Prepared medicated serumy by 20 male Wistar rats, the endothelial cells were seeded in both serum-free medium. VEGF expression was measured by immunohistochemistry. [Results] The medicated serum cell borders and nuclear structure clear nucleus color deeply stained, normal serum group the VEGF only a weak expression. [Conclusion] Yixin Dingji prescription can significantly promote VEGF expression, and it may be one of the mechanisms of treatment in coronary heart disease tachyarrhythmias. |
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