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| Effect of total Glucosides from Cornus officinalis and its medicated serum on the MSCs proliferation |
| Hits 1995 Download times 1745 Received:January 17, 2013 |
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| DOI
10.11656/j.issn.1673-9043.2013.02.11 |
| Key Words
total Glucosides from Cornus officinalis;medicated serum;mesenchymal stem cells;cell proliferation |
| Author Name | Affiliation | E-mail | | WANG Yan | Tianjin University of TCM, Tianjin 300193, China | | | SONG Chun-jing | Tianjin University of TCM, Tianjin 300193, China | | | SUN Xiu-yan | Tianjin University of TCM, Tianjin 300193, China | | | CAO Ying | Tianjin University of TCM, Tianjin 300193, China | | | LI Jing | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | virgue1978@sina.com | | BI Yue-ling | Tianjin University of TCM, Tianjin 300193, China | |
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| Abstract
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| [Objective] To discuss the effect of total Glucosides from Cornus officinalis and its medicated serum on proliferation of mesenchymal stem cells (MSCs).[Methods] MSCs were isolated from rat bone and cultured under total Glucosides from Cornus officinalis and its medicated serum, the proliferation effect on MSCs was detected with MTT.[Results] The 20% concentration of the TGC serum collected from rats 1 h later after intragastric infusion was proved to be the most effective concentration on the proliferation of MSCs, the 625 μg/mL concentration of the TGC was proved to be the most effective concentration on the proliferation of MSCs. [Conclusion] The total Glucosides from Cornus officinalis and its medicated serum can promote the proliferation of MSCs in rats. |
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