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Evaluation of extracted art of Rhizoma Picrorhizae based on multiple criteria comprehensively |
Hits 2096 Download times 1873 Received:April 27, 2013 |
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DOI
10.11656/j.issn.1673-9043.2013.03.09 |
Key Words
Rhizoma Picrorhizae;orthogonal test;picroside I;picroside II;percolation |
Author Name | Affiliation | E-mail | HOU Wen-bin | Tianjin University of TCM, Tianjin 300193, China Tianjin Institute of Pharmaceutical Research, Tianjin Engineering Laboratory of Quality Control Technology of TCM, National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine (Tianjin), Tianjin 300193, China | | ZHOU Fu-jun | Tianjin Institute of Pharmaceutical Research, Tianjin Engineering Laboratory of Quality Control Technology of TCM, National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine (Tianjin), Tianjin 300193, China | | SHAN Qi | Tianjin Institute of Pharmaceutical Research, Tianjin Engineering Laboratory of Quality Control Technology of TCM, National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine (Tianjin), Tianjin 300193, China | | LIU Chang-xiao | Tianjin Institute of Pharmaceutical Research, State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin 300193, China | liucx@tjipr.com |
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Abstract
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[Objective] To optimize the extraction process of Rhizoma Picrorhizae by an orthogonal experiment and to determine the best extraction parameters. [Methods] The L9(34) orthogonal test was employed based on a multiple criteria comprehensively evaluating the yields of picroside I, picroside II, and total extracts. [Results] The optimum extraction process was characterized as: soaking the crude rhizome powders for 24 h and percolating them with 1.5 mL/min of the flow rate and 16 folds of extraction volume were collected. [Conclusion] The extraction technique is stable and available.This study provides an experimental basis for the industrial production of Rhizoma Picrorhizae. |
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