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Literature analysis on dose of Shenfu injection in treating chronic heart failure |
Hits 2103 Download times 1586 Received:May 16, 2013 |
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DOI
10.11656/j.issn.1673-9043.2013.03.12 |
Key Words
Shenfu injection;chronic heart failure;dose;solvent |
Author Name | Affiliation | E-mail | LIU Chun-xiang | Tianjin University of TCM, Tianjin 300193, China | | WANG Yue | Tianjin University of TCM, Tianjin 300193, China | | ZHANG Shuo | Tianjin University of TCM, Tianjin 300193, China | | ZHANG Li | Tianjin University of TCM, Tianjin 300193, China | | XING Dong-mei | Tianjin University of TCM, Tianjin 300193, China | | REN Ming | Tianjin University of TCM, Tianjin 300193, China | renming2008@126.com |
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Abstract
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[Objective] To investigate the dose, solvent and solvent-dose of Shenfu injection in treating chronic heart failure. [Methods] The China Full-text Journal Database (CNKI), Jan,1993 to May,2012 was searched, and the clinical studies of Shenfu injection used intravenously for patients with chronic heart failure were found. [Results] The widely used dose of Shenfu injection intravenous infusion in chronic heart failure treatment was within 40~60 mL(80.01%), among them, 50 mL was the most widely applied(35.56%) with better security; 5% dextrose injection as solvent was commonly used(81.11%) and the mostly used dose was 250 mL(55.56%); for patients with diabetes, it was tended to and used 5% dextrose injection or 0.9% saline as solvent add insulin to solvent(50%). [Conclusion] Shenfu injection in therapy for patients with chronic heart failure are mostly applied as drug instruction. However, the research in basic and clinical dose-effect relationship should be strengthened. The optimal safe and effective dose should be explored. |
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