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| Effect of magnetic fields on human brain microvascular endothelial cell proliferation under normal and hypoxia condition |
| Hits 2137 Download times 1598 Received:September 26, 2013 |
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| DOI
10.11656/j.issn.1673-9043.2013.04.06 |
| Key Words
permanent magnetic field;human brain microvascular endothelial cell;cell proliferation |
| Author Name | Affiliation | E-mail | | MENG Qing-nan | Traditional Chinese Medicine Engineering Institute of Tianjin University of TCM, Tianjin 300193, China | | | WANG Yun-hua | Tianjin University of TCM, Tianjin 300193, China | | | ZHANG Hao-nan | Traditional Chinese Medicine Engineering Institute of Tianjin University of TCM, Tianjin 300193, China | | | YANG Lin | Tianjin University of TCM, Tianjin 300193, China | | | WANG Yi-min | Traditional Chinese Medicine Engineering Institute of Tianjin University of TCM, Tianjin 300193, China | wym@tjutcm.edu.cn |
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| Abstract
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| [Objective] To observe effect of different permanent magnetic fields on human brain microvascular endothelial cell（HBMEC） proliferation under normal and hypoxia conditions.[Methods] HBMEC were cultured in vitro under normal condition and hypoxia condition, experimental cells were divided into 10 groups, control group, ginkgo biloba injection（350 mg/L） group, different induction magnetic field groups （3.4, 5.6, 13.8, 27.8, 52.6, 107.0, 178.9, 292.2 mT）, each group was collected specimens 48 h after planking, MTT method was used to measure cell proliferation. [Results] Compared with control group, the drug group was statistically different（P<0.05） under normal condition and hypoxia condition, magnetic field groups were no statistically different（P>0.05）; there was no statistical difference between magnetic field groups（P>0.05）.[Conclusion] Magnetic field groups with magnetic induction 3.4,5.6,13.8,27.8,52.6,107.0,178.9,292.2 mT have no effect on proliferation of HBMEC cultured under normal or hypoxia condition. |
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