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| Influence of different quantity of moxibustion on colon damage and serum IgG, IgA, IgM level in rats with crohn’s disease |
| Hits 2228 Download times 2240 Received:October 16, 2013 |
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| DOI
10.11656/j.issn.1673-9043.2014.01.08 |
| Key Words
moxibution;Crohn’s Disease;rats;the integral score of intestinal injury;immune globulin |
| Author Name | Affiliation | | WANG Jing | Anhui College of TCM, Hefei 230038, China | | XIA Xiao-hong | Anhui College of TCM, Hefei 230038, China | | YE Min | Anhui College of TCM, Hefei 230038, China | | JANG Li | Anhui College of TCM, Hefei 230038, China | | WU Si-dan | Anhui College of TCM, Hefei 230038, China |
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| Abstract
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| [Objective] To explore the effects and mechanism in treating Crohn's Disease (CD) with different quantity of moxibustion (moxi). [Methods] Forty-five rats with CD were divided into 5 groups: normal group, model group, moxi A group, moxi B group and moxi C group. At the fourteenth days after disposing, their integral score of the colon damage and the serum IgG, IgA, IgM level were observed. [Results] The integral score of the intestinal injury and the serum IgG, IgA and IgM level in model group was higher than that in the rest of group (P<0.01), moxi can lower the integral score of colon damage, the serum IgG, IgA and IgM level and was benefited for the colon inflammatory response. But the effect of moxi for 5 min was not significant, the effect of moxi for 15 min was as significant as the effect of moxi for 25 min (P>0.01). [Conclusion] Proper moxibustion quantity can significantly lower the integral score of colon damage and the serum IgG, IgA and IgM level, improve the immune system, alleviate the colon inflammatory changes in rats with CD. |
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