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| Research on dissolution rule of medicinal components of rawand processed Corydalis Rhizoma pieces in compound prescriptions |
| Hits 2156 Download times 1777 Received:January 24, 2014 |
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| DOI
10.11656/j.issn.1673-9043.2014.03.15 |
| Key Words
Corydalis Rhizoma;tetrahydropalmatine;dehydrocorydaline;UPLC;dissolution |
| Author Name | Affiliation | E-mail | | WU Zi-jun | Tianjin University of Traditional Chinese medicine, Tianjin 300193, China | | | ZHANG Jing-yi | Tianjin University of Traditional Chinese medicine, Tianjin 300193, China | | | LUO Chen-yan | Tianjin University of Traditional Chinese medicine, Tianjin 300193, China | | | YU Shu-juan | Tianjin University of Traditional Chinese medicine, Tianjin 300193, China | | | DOU Zhi-ying | Tianjin University of Traditional Chinese medicine, Tianjin 300193, China | zhiyingdou@163.com |
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| Abstract
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| [Objective] To explore the dissolution rule of alkaloids of raw and processed Corydalis Rhizoma pieces in different compound prescriptions. [Methods] The raw and processed Corydalis Rhizoma pieces were put respectively in Jinlingzi powder, Yuanhu Zhitong tablets and Yanhusuo decoction. UPLC method was used to detect content of alkaloids of the water extract of the three formula prescriptions for getting the dissolution rate of alkaloids. [Results] Compared with single raw and processed Corydalis Rhizoma the content of tetrahydropalmatine of the water extract of the three formula prescriptions was not significantly improved and also had the same rule to the content of dehydrocorydaline. [Conclusion] The dissolution rate of alkaloids of raw and processed Corydalis Rhizoma has little difference in the three formula prescriptions. |
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