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| Effects of Yiqi Huoxue Jiedu formula on the ovarian cancer patients with neuropathy caused by chemotherapy containing paclitaxel |
| Hits 1721 Download times 2233 Received:July 20, 2014 |
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| DOI
10.11656/j.issn.1673-9043.2014.05.06 |
| Key Words
Yiqi Huoxue Jiedu formula;ovarian cancer;paclitaxel;neurotoxicity |
| Author Name | Affiliation | E-mail | | MA Dan | Oncology Department, Guang'anmen Hospital, China Academy of Medical Sciences, Beijing 100053, China | | | ZHENG Qiao | Beijing University of Chinese Medicine, Beijing 100029, China | | | YAN Hui-ling | Beijing University of Chinese Medicine, Beijing 100029, China | | | LU Wen-ping | Oncology Department, Guang'anmen Hospital, China Academy of Medical Sciences, Beijing 100053, China | lu_wenping@sina.com |
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| Abstract
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| [Objective] To observe the effect of Yiqi Huoxue Jiedu formula on the ovarian cancer patients with neuropathy caused by chemotherapy containing paclitaxel.[Methods] The 90 ovarian cancer patients who met the criteria received Yiqi Huoxue Jiedu formula by mouth and soaking feet, respectively. One month later, the differences of neuropathy degree and peripheral nerve conduction velocity before and after treatment were analyzed. [Results] The peripheral neurotoxicity occurrence of the cases of two kinds of accompanying symptoms reduced, and the differences of two kinds of accompanying symptoms were statistically significant(P<0.01). After treatment, the motion and sensory nerves conduction velocity of median nerve and peroneal nerve were all changed, except sensory nerve conduction velocity of the damp pathogen of the median nerve(P>0.05), the differences before and after treatment were statistically significant(P<0.05). [Conclusion] Combination of herbs of Yiqi Huoxue Jiedu formula by mouth and by soaking feet could improve neuropathy of ovarian patients caused by chemotherapy containing paclitaxel. |
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