|
| External anti-bacterial effects of bakuchiol and baicalin on pathogenic bacteria of acne |
| Hits 2379 Download times 1612 Received:May 26, 2014 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2014.05.12 |
| Key Words
bakuchiol;baicalin;staphylococcus epidermidis;propionibacterium acnes;colony counting method;anti-bacterial effect |
| Author Name | Affiliation | E-mail | | DENG Xin-huan | Scholars and Innovative Research Team in University(PCSIRT)Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | WANG Ya-jing | Scholars and Innovative Research Team in University(PCSIRT)Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | yajing022@163.com | | YU Yue | Scholars and Innovative Research Team in University(PCSIRT)Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | ZHENG Yin | Scholars and Innovative Research Team in University(PCSIRT)Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | |
|
| Abstract
|
| [Objective] To study tha external anti-bacterial activity of bakuchiol and baicalin in acne.[Methods] The colony counting method was applied to determine the inhibitory ratio against staphylococcus epidermidis and propioni-bacterium acnes growth by adding the mixed solution with different concentrations of bakuchiol and bakuchiol-baicalin. [Results] The inhibitory ratios against staphylococcus epidermidis and propionibacterium acnes growth were 100.0% and 61.1% with 2 560 mg/L bakuchiol solution. Two kinds of acne bacteria inhibitory rate were 100.0% under the mixed solutions with the bakuchiol concentration of 2 560 mg/L and baicalin 800 mg/L. In particular, the propionibacterium acnes inhibitory rate was improved for 1.64 times than single bakuchiol.[Conclusion] The increasing of the inhbitory rate in combination of a certain amount of bakuchiol and baicalin indicates that they can perform a synergism function,which can significantly enhance the anti-acne bacterial effects,revealing the necessity and rationality on the inhibition against staphylococcus epidermidis and propionibacterium acnes growth. |
|
|
|
|
|
