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Clinical study on treatment of perennial allergic rhinitis of with the combination of Yifei Jianpi method and dog-day acupoint application
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DOI   10.11656/j.issn.1673-9043.2015.02.04
Key Words   allergic rhinitis;Yifei Jianpi method;dog-day acupoint application;IL-4
Author NameAffiliation
YANG Mei-feng Fujian University of Traditional Chinese Medicine, Fuzhou 350122 
ZENG Yi-sheng E. N. T. department, Second People's Hospital of Fujian Province, Fuzhou 350003 
LAI Chang-sha Fujian province people's Hospital of Traditional Department of Internal Medicine, Fuzhou 350004 
Abstract
    [Objective] To observe the therapy effect with the combination of Yifei Jianpi Method and dog-day acupoint application of perennial allergic rhinitis(PAR),and the changes of serum interleukin-4(IL-4). [Methods] Sixty patients with perennial allergic rhinitis are randomly divided into two groups with 30 patients eath.The treatment group was treated with the combination of Yifei Jianpi Method and dog-day acupoint application,while control group was treated with cetirizine tables only. Serum level of IL-4 were measured before treatment,at the final treatment and 3 months after treatment.Clinical syndromes and physical signs were observed.[Results] Grade of physical signs and serum lever of IL-4 weren't different after the final treatment between the treatment group and the control group(P>0.05). Grade of clinical symptoms and therapy effect were different after the final treatment between the treatment group and the control group(P<0.01). Grade of physical signs weren't different 3 months after treatment between the treatment group and the control group(P>0.05).Grade of clinical symptoms and therapy effect and serum lever of IL-4 were different after 3 months treatment between the treatment group and the control group(P<0.01).[Conclusion] The combination of Yifei Jianpi method and dog-day acupoint application had extract curative effect in PAR,it was related with which can reduce serum level of IL-4. It can adjust the imbalance of Th1/Th2 and further improve immune state for long time in PAR patients.

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