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| The influence of early application of Shenfu injection on procalcitionin and brain natriuretic peptide in elderly patients with severe pneumonia |
| Hits 1732 Download times 2008 Received:November 24, 2014 |
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| DOI
10.11656/j.issn.1673-9043.2015.02.05 |
| Key Words
Shenfu injection;severe pneumonia;procalcitionin;brain natriuretic peptide |
| Author Name | Affiliation | E-mail | | LI Jia-ning | Respiratory Department, The People's Hospital of Tangshan, Tangshan 063000, China | | | LI Xiu-zhi | Respiratory Department, Affiliated Hospital of Hebei United University, Tangshan 063000, China | | | GUO Xia | Respiratory Department, Affiliated Hospital of Hebei United University, Tangshan 063000, China | | | WANG Hong-yang | Respiratory Department, Affiliated Hospital of Hebei United University, Tangshan 063000, China | zyning789@126.com | | HAO Sheng-wang | Respiratory Department, The People's Hospital of Tangshan, Tangshan 063000, China | |
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| Abstract
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| [Objective] To investigate the influence of early application of Shenfu injection on procalcitionin(PCT)and brain natriuretic peptide (BNP) in elderly patients with severe pneumonia. [Methods] Eghtity-four elderly patients with severe pneumonia were divided into Shenfu injection group (42 cases) and control group (42 cases).The control group received basic treatment (anti-inflammatory and nutritional support etc). While the Shenfu injection group received early application of Shenfu injection therapy besides basic treatment. PCT and BNP level were measured before and after 1 d, 3 d, 5 d;and the effects of early application of Shenfu injection on PCT and BNP in elderly patients with severe pneumonia were analyzed combining the patients condition within 7 d. [Results] Compared with the control group, there were no significant difference in the PCT and BNP level after 1 d in Shenfu injection group (P>0.05). The PCT and BNP level were lower in Shenfu injection group than those in control group after 3d and 5d (P<0.05). The score of APACHE II was better than those in control group after 3 d and 5 d (P<0.05).Ten cases were improved, 17cases progressed and 15 cases died in the control group, while 19 cases were improved, 14 cases progressed and 9 cases died in Shenfu injection group after 7 d. Compare with the traditional Chinese medicine syndromes between the two groups, the total effective rate (90.5%) in Shenfu injection group was higher than in control group. [Conclusion] Early application of Shenfu injection can inhibit the PCT and BNP level in elderly patients with severe pneumonia and improve the prognosis. |
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