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| Isolation and identification of chemical constituents from Nelumbinis Folium(Ⅲ) |
| Hits 1816 Download times 1712 Received:December 14, 2014 |
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| DOI
10.11656/j.issn.1673-9043.2015.02.08 |
| Key Words
Nelumbinis Folium;chemical constituents;structure identification |
| Author Name | Affiliation | E-mail | | XIA Ming-hui | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | PENG Shuang | Qinghai Lake Pharmaceutical Company Limited, Xining 810000, China | | | ZHAO Jing | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | HAN Li-feng | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | ZHANG Yi | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | WANG Tao | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | wangt@263.net |
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| Abstract
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| [Objective] To investigate the chemical constituents of the lotus leaf for futher research and development. [Methods] The chemical components were obtained by using several chromatographies, such as silica gel, ODS, Sephadex LH-20 and PHPLC, and their structures were identified by the physico-chemical methods, MS, NMR spectra and comparing with literatures. [Results] Six compounds were isolated from 70 % ethanol extract of lotus leaves and identified as sarmentol F (1); (3S, 5R, 6S, 7E, 9R)-7-megastigmene-3,6,9-triol (2); (3S, 5R, 6R, 7E)-3, 5, 6-trihydroxy-7-megastigmen-9-one (3); 3S, 5R-dihydroxy-6R, 7-mestigmadien-9-one (4); 3S, 5R-dihydroxy-6S, 7-mestigmadien-9-one(5), and R-(-)-dehydrovomifoliol (6). [Conclusion] Compounds 1～6 are obtained from Nelumbo Adans. for the first time. |
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