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| Inhibitory activity of flavonoids isolated from Exochorda serratifolia S. Moore. on α-glucosidase |
| Hits 2216 Download times 2315 Received:February 05, 2014 |
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| DOI
10.11656/j.issn.1673-9043.2014.10 |
| Key Words
Exochorda serratifolia S. Moore.;flavonoids;α-glucosidase;inhibitory activity |
| Author Name | Affiliation | | LI Gu-yue | The First Hospital of China Medical University, Shenyang 110000, China
Pharmacy College of China Medical University, Shenyang 110000, China | | LIU Jia-xin | The First Hospital of China Medical University, Shenyang 110000, China
Pharmacy College of China Medical University, Shenyang 110000, China | | CAI Qian | Pharmacy College of Liaoning University of Traditional Chinese Medicine, Dalian 116600, China |
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| Abstract
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| [Objective] To investigate the inhibitory activity of flavonoids isolated from Exochorda serratifolia S. Moore. leaves on α-glucosidase.[Methods] Inhibitory activity of α-glucosidase was screened by the 96-microplate-based method.[Results] The flavonoids showed inhibitory activity on α-glucosidase. Among them, luteolin, luteolin-7-O-β-D-neospheroside, apigenin, apigenin-7-O-β-D-neospheroside, quercetin, quercetin-3-O-β-D-glucoside showed stronger inhibitory activity than acarbose.[Conclusion] Flavonoids may be the substances basis of Exochorda serratifolia S. Moore. leaves with inhibitory activity of α-glucosidase. |
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