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| Isolation and structural identification of Flavonones from Althaea rosea flowers |
| Hits 1704 Download times 1203 Received:April 15, 2015 |
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| DOI
10.11656/j.issn.1673-9043.2015.04.11 |
| Key Words
Althaea Rosea;constituents;flavonones;structural identification;absolute configuration |
| Author Name | Affiliation | E-mail | | CHAO Li-ping | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | CHEN Qiu | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | SHI Ping-ping | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | LI Xiao-xia | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | WANG Tao | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | ZHANG Yi | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | zhwwxzh@263.net |
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| Abstract
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| [Objective] Continue to study the constituents of Althaea rosea. [Methods] The chemical constituents were obtained through ODS, Silica gel column chromatorgraphies and PHPLC chromatorgraphy and identified by chemical and kinds of spectral analysis. [Results] Eight flavonones were obtained and determined as (2R,3R)-dihydrokaempferol-4'-O-β-D-glucopyranoside (1), (2R,3R)-(+)-taxifolin (2), (2R,3R)-taxifolin-3'-O-β-D-glucopyranoside (3), (2R,3R)-taxifolin-7-O-β-D-glucopyranoside (4), (2R,3R)-dihydromyricetin-3'-O-glucoside (5), (2R,3R)-3,5,6,7,4'-pentahydroxyflavanonol (6), (2S)-4',5,7-trihydroxy flavanone (7), choerospondin (8), respectively. [Conclusion] Compounds 3-6 are obtained from Althaea genus firstly. On the other hand, the absolute configurations of all isolates are determined by CD spectrum. |
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