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| Effect of prevention and treatment of Longzhipeifang granule on coronary artery restenosis after PCI operation |
| Hits 1810 Download times 1699 Received:May 25, 2015 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2015.05.03 |
| Key Words
Longzhipeifang granule;PCI;restenosis |
| Author Name | Affiliation | E-mail | | ZHOU Wei | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | ZHAO Xiao-bing | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | ZHOU Mei | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | FU Ling | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | CHEN Xi | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | TANG Jian-hua | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | WAN Gui-lai | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | WANG Cheng-peng | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | | | ZHANG Jian-hong | Tongliang Hospital of Traditional Chinese Medicine, Tongliang 402560, China | 1012829460@qq.com |
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| Abstract
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| [Objective] To observe effect and safety of prevention and treatment of Longzhipeifang granule on coronary artery restenosis after PCI operation. [Methods] According to indication for PCI and PCI after the operation success and TCM syndrome differentiation for chest pain (kidney deficiency and phlegm, qi stagnation and blood stasis type) were randomly divided into experimental group and control group, in the control group conventional use of antithrombotic and antiplatelet agents, lipid-lowering, expansion of coronary plaque stability after PCI treatment, in the experimental group on the basis of the control group addition with Longzhipeifang granule, the course of treatment was 6 months, evaluation of effect and safe in patients of PCI after coronary restenosis. [Results] Longzhipeifang granule had better effect than the control group on stent restenosis occurrence, TCM symptoms, angina pectoris, high sensitivity C-reactive protein (CRP) and the serum total bilirubin, and there were no adverse events. [Conclusion] On the basis of routine use of antithrombotic and antiplatelet agents, lipid-lowering, expansion of coronary plaque stability,Longzhipeifang Granule has better effect in prevention and treatment of coronary restenosis after PCI, even in complicated with diabetes, has better effect than the control group in the TCM symptoms, angina pectoris, high sensitivity C-reactive protein and serum total bilirubin, also it is more safe. |
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