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| Cell membrane chromatography and application of it in screening active components and security evaluation of traditional Chinese medicine |
| Hits 1724 Download times 1465 Received:July 15, 2015 |
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| DOI
10.11656/j.issn.1673-9043.2015.06.15 |
| Key Words
cell membrane chromatography;traditional Chinese medicine;activity screening;security evaluation |
| Author Name | Affiliation | E-mail | | CHEN Ying | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | BAI Zi-song | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China
Tianjin International Joint Academy of Biomedicine, Tianjin 300457, China | | | ZHU Yan | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | ZHANG Peng | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | zhp8270@sina.com.cn |
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| Abstract
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| Cell membrane chromatography(CMC), which imitates interaction of drug and target in vitro, has been widely used for screening active components. This paper reviewed the development process of CMC technology, as well as summarized the diseases, targets, cell types, tradional Chinese medicine types and chemical composition types involved in the past screening research. Also we discussed the limitation of CMC in the application field. |
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