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| Experiment study of Huangdi Jixian decoction on FBG and HbA1c in type 2 diabetes |
| Hits 3129 Download times 2340 Received:September 23, 2015 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2016.01.07 |
| Key Words
Type 2 diabetes;Huangdi Jixian decoction;FBG;HbA1c |
| Author Name | Affiliation | E-mail | | YANG Li-na | The Affiliated Traditional Chinese Medicine Hospital of Kunming General Hospital of Chengdu Military Command, Kunming 650032, China | | | LUO Zhi-hong | The Affiliated Traditional Chinese Medicine Hospital of Kunming General Hospital of Chengdu Military Command, Kunming 650032, China | | | LUAN Xiao-wen | The Affiliated Traditional Chinese Medicine Hospital of Kunming General Hospital of Chengdu Military Command, Kunming 650032, China | | | NING Yu-qing | The Affiliated Traditional Chinese Medicine Hospital of Kunming General Hospital of Chengdu Military Command, Kunming 650032, China | | | LI Fu-qiang | The Affiliated Traditional Chinese Medicine Hospital of Kunming General Hospital of Chengdu Military Command, Kunming 650032, China | | | NING Ya-gong | The Affiliated Traditional Chinese Medicine Hospital of Kunming General Hospital of Chengdu Military Command, Kunming 650032, China | kmnyg@126com |
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| Abstract
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| [Objective] To observe the effects of Huangdi Jixian decoction guided by “reinforcing and reducing, adjustment the balance” method on the FBG and HbA1c in type 2 diabetic rats. [Methods] Sixty male SD rats of clean grade, randomly selected 10 rats as the normal control group, the remaining 50 of given high fat diet add disposable small dose of intraperitoneal injection of STZ add stress to induce rat model of type 2 diabetes mellitus. After the success of modeling, 50 rats were randomly divided into model group, western medicine group, Chinese medicine treatment of low, medium and high dose groups, 10 rats in each group. All groups were treated 8 weeks, before and after administration of the body weight, the determination of FPG, HbA1c were administered. [Results] Western medicine treatment group, Chinese herbal medicine in high, medium and low dose group rats were improved in general condition after treatment. The weight in the high dosage group of Chinese medicine increased significantly than those in the other four groups (P<0.05). The FBG in the western medicine treatment group, Chinese medicine of high, middle dose group were decreased significantly than model group (P<0.05 or 0.01). Traditional Chinese medicine of high dose can significantly reduced HbA1c.[Conclusion] Huangdi Jixian decoction can obviously improve the diabetic rats in general condition, significantly reduced blood glucose and HbA1c. |
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