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| The introduction and evaluation of patient preference randomized controlled trials |
| Hits 1728 Download times 2432 Received:October 11, 2015 |
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| DOI
10.11656/j.issn.1673-9043.2016.01.17 |
| Key Words
patient preferences randomized controlled trials;method;evaluation |
| Author Name | Affiliation | E-mail | | CHEN Xin-lin | School of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | LIU Feng-bin | The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510405, China | | | MO Chuan-wei | School of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | HOU Zheng-kun | The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510405, China | | | QIU Zhen-wen | The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510405, China | | | XU Qian | School of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | LI Xian-tao | School of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou 510006, China | lixiantao@gzucmeducn |
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| Abstract
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| In order to solve the problems of randomized controlled trials, such as patient preferences, ethics and compliance, researchers have proposed patient preference randomized controlled trials. This study mainly introduces some designs: patient preference two-stage trial design (Wennberg design, Rücker design), comprehensive cohort design (Brewin design and Olschewski design), prerandomized design and Korn design. This study also evaluated the advantages and disadvantages of these designs, so that researchers and clinical doctors could select the appropriate designs according to the research purpose and the characteristics of the disease. |
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