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| Study on the relationship between TCM syndrome differentiation and immune inflammation indexes, cytokines in psoriatic arthritis |
| Hits 1686 Download times 2351 Received:December 29, 2015 |
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| DOI
10.11656/j.issn.1673-9043.2016.02.04 |
| Key Words
psoriatic arthritis;syndromes;Tumor Necrosis Factor-alpha;IL-17;IL-23 |
| Author Name | Affiliation | E-mail | | XIN Hao-yang | Chinese PLA Medical School,Beijing 100853, China
Chinese PLA General Hospital, Beijing 100853, China | | | WANG Peng-peng | Chinese PLA 252 Hospital, Baoding 071000,Hebei Province, China | | | MA Yu-chen | Chinese PLA 252 Hospital, Baoding 071000,Hebei Province, China | myc252@126.com |
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| Abstract
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| [Objective] To investigate the relationship between different syndromes and immune inflammatory markers, cytokines in psoriatic arthritis (PsA). [Methods] Sixty-two cases of patients diagnosed with PsA were divided into damp-heat syndrome, cold syndrome and YIN-deficiency and blood-dryness syndrome according to Chinese medicine syndrome differentiation criteria. Testing each group of patients ESR、CRP、IgA、IgG、IgM、TNF-α、IL-17、IL-23, study the correlation between indexes and syndromes. [Results] 3 groups of patients IgA, IgG, IgM levels were above the normal range, but no statistically significant difference in each group (i>P> 0.05), damp syndrome patients ESR, CRP, TNF-ɑ, IL-17, IL-23 levels were significantly higher than cold syndrome, YIN-deficiency and blood-dryness syndrome patients, the difference was statistically significant (P< 0.01). [Conclusion] There were association between the degree of disease activity,immune function and syndrome in patients with PsA. Inflammatory markers and cytokines may be used as microscopic indicators of TCM dialectical type. |
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