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Clinical analysis of 36 cases of idiopathic central precocious puberty treated by traditional Chinese medicine and Western medicine
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DOI   10.11656/j.issn.1673-9043.2016.02.05
Key Words   ICPP;GnRHa;Dabuyin Wan;clinical analysis
Author NameAffiliation
QI Hui-ju Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
ZHANG Xue-yuan Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
XIANG Rong Tianjin Nankai Hospital, Tianjin 300100, China 
Abstract
    [Objective] To compare the clinical effect of traditional Chinese medicine and Western medicine(TCM-WM) and Western medicine in treatment of girls with idiopathic central precocious puberty(ICPP). [Methods] Tianjin Nankai hospital pediatric endocrinology clinic 72 patients with diagnosis of ICPP girl children were selected randomly assigned to TCM-WM group and the western medicine group. TCM-WM group were treated with traditional Chinese medicine (for nourishing yin and purging fire, to Dabuyin Wan based square to add and subtract), and auxiliary gonadotropin releasing hormone analogue (GnRHa); the western medicine group was treated with conventional GnRHa. Evaluation of efficacy and economic burden after two groups were treated for a year and a half, statistics of two groups total effective for the treatment of ICPP. [Result] the total effective rate of the TCM-WM group was 77.8%, the total effective rate was 80.56% in the western medicine group, the difference was not statistically significant between the two groups. However, the economic burden of the TCM-WM group was significantly lower than that in the western medicine group, and the adverse reactions were less than that of the western medicine group. [Conclusion] TCM-WM treatment of girls ICPP in the clinical efficacy and conventional treatment of Western medicine, and the inhibition of the growth axis, the adverse reactions less, the economic burden is smaller.

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