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| The orthogonal experiment method to optimize the extraction process of senna |
| Hits 2164 Download times 2254 Received:November 14, 2015 |
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| DOI
10.11656/j.issn.1673-9043.2016.02.13 |
| Key Words
senna;sennoside;sennoside A;sennoside B;extraction process |
| Author Name | Affiliation | E-mail | | JIN Shi-shi | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | NIU Huan-yun | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | DING Hui | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | WU Jie | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YU He-shui | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Wei | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | CAO Man | Tianjin Zhongyi Pharmaceutical Co.Ltd,Tianjin 300193, China | | | SONG Xin-bo | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin Zhongyi Pharmaceutical Co.Ltd,Tianjin 300193, China | songxinbo@tjutcm.edu.cn |
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| Abstract
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| [Objective] To select the best extraction process of sennoside from senna. [Methods] To establish the method for simultaneous determination of Sennoside A and Sennoside B, the method utilizes the content of Sennoside A and Sennoside B as a quality control. Based on the single factor, the best extraction process is selected by orthogonal test. [Results] The best process for extraction was 10 fold 0.5% sodium bicarbonate was used to extract Sennoside under 60 ℃ for an hour. [Conclusion] The developed process is stable and reliable, and can be readily utilized for related research and actual production. |
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