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Clinical analysis of TCM etiology and pathogenesis of polycystic ovarian syndrome
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DOI   10.11656/j.issn.1673-9043.2016.03.04
Key Words   polycystic ovarian syndrome;syndrome element;disease location;nature of disease;etiology and pathogenesis
Author NameAffiliation
KE Yin-xia Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China 
WANG Chang-song Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China 
LV Shao-guang Department of Traditional Chinese Medicine, Provincial Clinical College of Fujian Medical University, Fuzhou 350122, China 
Abstract
    [Objective] Discuss the TCM etiology and pathogenesis of polycystic ovarian syndrome (PCOS). [Methods] One hundred and one cases of patients with PCOS were selected, and the method of differentiation of symptoms and signs based on symptom factors differentiation was adopted to analyze these cases. The frequency and integration of syndrome elements of disease location and nature were studied. [Results] In these cases, the integration value of syndrome elements in different disease locations ranked from great to small as follows: uterus, kidney, liver, spleen, mind and large intestine. Especially, the values for uterus and kidney had significant difference comparing with other syndrome elements (P<0.01). Also, the values for liver and spleen had significant difference comparing with other syndrome elements (P<0.05). In the asthenia syndrome, the integration value of Qi-deficiency was highest, which had a significant difference (P<0.01) comparing with other syndromes (the values of these syndromes ranked for great to small as follows: yin-deficiency, yang-deficiency, blood-insufficiency and kidney-jing deficiency). Moreover, the values for yin-deficiency and yang-deficiency had a significant difference (P<0.05) comparing with other syndromes. In the excess syndrome, the integration values ranked from great to small as follows: Qi stagnation, blood-stasis, phlegm, dampness and cold. Difference between Qi stagnation and other syndromes had statistical significance (P<0.01). In addition, the values for blood-stasis, phlegm and dampness were also different with other syndromes, which had statistical significance (P<0.05). [Conclusion] The pathological viscera of PCOS are mainly uterus and kidney, and its pathogenesis comes down to kidney deficiency accompanied with Qi stagnation, blood-stasis and phlegm-damp etc., and is essential empty and out solid.

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