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| The expressions and changes of fibrinogen hypersensitive C reactive protein and the complement system in patients of acute myocardial infarction and blood stasis syndrome |
| Hits 2162 Download times 2018 Received:April 26, 2016 |
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| DOI
10.11656/j.issn.1673-9043.2016.04.05 |
| Key Words
acute myocardial infarction;blood stasis syndrome;fibrinogen;hypersensitive C reactive protein;complement system |
| Author Name | Affiliation | E-mail | | SHAO Ai-hong | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Internal Medicine-Cardiovascular Department, Tianjin People's Hospital, Tianjin 300191, China | | | QI Xin | Internal Medicine-Cardiovascular Department, Tianjin People's Hospital, Tianjin 300191, China | qixinx2011@126.com | | JIA Wen-jun | Internal Medicine-Cardiovascular Department, Tianjin People's Hospital, Tianjin 300191, China | | | LI Qi | Internal Medicine-Cardiovascular Department, Tianjin People's Hospital, Tianjin 300191, China | |
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| Abstract
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| [Objective] To investigate the expression of fibrinogen hypersensitive C-reactive protein, and complement system in the patients with acute myocardial infarction and blood stasis syndrome. [Methods] Detect the levels of fibrinogen, hypersensitive C reactive protein, and the complement system including C3, C4, C5b-9 for 72 patients with acute myocardial infarction including blood stasis and non-blood stasis syndrome, the same as 33 healthy control group, and analyse the correlation between the indexes above and blood stasis syndrome. [Results] Comparing with the control group, levels of fibrinogen, hypersensitive C reactive protein, and the complement system including C3, C4, C5b-9 in patients of AMI were significantly higher than those in control group, and levels in blood stasis syndrome group were higher than in non-blood stasis syndrome group;there were positive correlation between blood stasis and hs-CRP, FIB and D-dimer(r=0.239, r=0.402, r=0.199, P<0.05); there were positive correlation between score of GRACE and the levels of blood stasis syndrome, hs-CRP(r=0.309, r=0.376, P<0.05). [Conclusion] There are certain degree of inflammatory reaction and high coagulation state in patients with acute myocardial infarction, which express more obviously in blood stasis group;there are positive correlation between blood stasis group hs-CRP, FIB and D-dimer;early dialectical therapy for blood stasis syndrome in patients of AMI with a high risk can reduce the risk of the occurrence of acute cardiovascular events. |
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