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| HS-SPEM-GC-MS analysis of the volatile components of Dan-lou tablets |
| Hits 2011 Download times 1737 Received:April 02, 2016 |
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| DOI
10.11656/j.issn.1673-9043.2016.04.10 |
| Key Words
Dan-lou tablet;volatile oil;GC-MS analysis |
| Author Name | Affiliation | E-mail | | ZHANG Na | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China
Tianjin International Joint Academy of Biomedicine, Research and Development Center of Traditional Chinese Drug, Tianjin 300457, China | | | LI Lin | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | GAO Shan | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | ZHU Yan | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | | | WANG Jia-ming | Tianjin University of Science and Technology, Engineering College of Biology, Tianjin 300457, China | | | ZHANG Peng | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | zhp8270@sina.com.cn | | YU Chun-quan | Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193, China | ycq-4@163.com |
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| Abstract
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| [Objective] Using gas chromatography-mass spectrometry technology(GC-MS) to identify the chemical composition of volatile oil of Dan-lou tablets. [Method] In this paper, volatile components of Dan-lou tablets were extracted by headspace solid phase microextraction (HS-SPEM). Their structures were identified based GC-MS database combined with Retention Index (KI) calculated. [Results] Fourty-four kinds of volatile oil compounds were identified from Dan-lou tablet, which accounted 72.46% of the total volatile oil components. The ingredients which have content more than 5% were Ligustilide (17.49%), β-Elemenone (11.07%), (-)-Spathulenol(8.95%), 3-butenyl-1(3H)-isobenzofuranone (5.502%) et al. [Conclusion] Volatile components of Dan-lou tablet are fully analyzed. The identifiedcompounds have multiple activities according the prevent reports. This article provides a scientific basis for quality control and further pharmacological research of Dan-lou tablets. |
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